094 Anakinra in treatment resistant hospitalised acute polyarticular gout
نویسندگان
چکیده
منابع مشابه
Acute polyarticular gout.
We report here on 41 male patients with acute polyarticular gout seen in 3 years. Acute polyarticular gout continues to masquerade as other commoner rheumatological disorders such as septic arthritis, rheumatoid arthritis, degenerative joint disease, and even hemiparesis. Almost all of these patients had clues to the diagnosis of acute gout in their medical history. These clues included a past ...
متن کاملManagement of treatment resistant inflammation of acute on chronic tophaceous gout with anakinra.
W e report a 74-year-old man with acute on chronic tophaceous gout in whom conventional treatments failed but who responded to treatment with the interleukin-1 receptor antagonist, anakinra. The patient presented in February 2004 with a severe flare of gout. Multiple joints were swollen, including the right fifth proximal interphalangeal (PIP), the left fourth PIP, and the first metatarsophalan...
متن کاملA pilot study of IL-1 inhibition by anakinra in acute gout
Monosodium urate crystals stimulate monocytes and macrophages to release IL-1beta through the NALP3 component of the inflammasome. The effectiveness of IL-1 inhibition in hereditary autoinflammatory syndromes with mutations in the NALP3 protein suggested that IL-1 inhibition might also be effective in relieving the inflammatory manifestations of acute gout. The effectiveness of IL-1 inhibition ...
متن کاملtreatment of colchicine-resistant familial mediterranean fever with anakinra
conclusions this case showed the effect of additional anakinra on children with fmf who were colchicine resistant. case presentation herein was reported a colchicine non-responsive patient with accurate diagnosis and early treatment of fmf. she had presented with recurrent and persistent acute abdominal pain attacks and several abdominal surgeries. addition of recombinant interleukin-1 receptor...
متن کاملErosive polyarticular tophaceous gout: an unusually deforming and destructive presentation.
To cite: Redmond CE, Babiker A, Redmond PL, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013202335 DESCRIPTION An 87-year-old man was referred to our rheumatology clinic for assessment of painful, swollen and deformed fingers. He had a history of longstanding, but suboptimally treated gout, which had resulted in previous amputation of his left middle fi...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2018
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/key075.318